Erythema nodosum - Nodozni Eritem
☆ V rezultatih raziskave Stiftung Warentest iz Nemčije leta 2022 je bilo zadovoljstvo potrošnikov z ModelDermom le nekoliko nižje kot s plačanimi telemedicinskimi svetovanji.
Kaže se kot boleč eritematozen vozlič na nogi.
References
Erythema nodosum je najpogostejša vrsta panikulitisa, za katero so značilni boleči rdeči vozlički, ki se večinoma nahajajo na spodnjih nogah. Njegov natančen vzrok ostaja neznan, vendar se zdi, da je posledica pretiranega odziva na različne sprožilce. Čeprav je njegov izvor pogosto negotov, je nujno, da izključite druge osnovne bolezni, preden postavite diagnozo primary erythema nodosum. Lahko kaže na pojav sistemskih bolezni, kot so okužbe, vnetja, rak ali reakcije na zdravila. Pogosti sprožilci vključujejo strep infections, tuberculosis, sarcoidosis, Behçet's disease, inflammatory bowel disease, certain medications, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Erythema nodosum is the most common form of panniculitis and is characterized by tender erythematous nodules mainly in the lower limbs on the pretibial area. The exact cause of erythema nodosum is unknown, although it appears to be a hypersensitivity response to a variety of antigenic stimuli. Although the etiology is mostly idiopathic, ruling out an underlying disease is imperative before diagnosing primary erythema nodosum. Erythema nodosum can be the first sign of a systemic disease that is triggered by a large group of processes, such as infections, inflammatory diseases, neoplasia, and/or drugs. The most common identifiable causes are streptococcal infections, primary tuberculosis, sarcoidosis, Behçet disease, inflammatory bowel disease, drugs, and pregnancy.
Panniculitis se nanaša na raznolik nabor vnetnih stanj, ki prizadenejo maščobno tkivo pod kožo. Ta stanja so redka pri otrocih. Panniculitis je lahko glavna težava v sistemskem stanju ali sekundarna reakcija na dejavnike, kot so okužba, poškodba ali določena zdravila. Ne glede na vzrok ima večina vrst panniculitis podobne simptome, vključno z bolečimi rdečimi vozlički pod kožo.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitides form a heterogenous group of inflammatory diseases that involve the subcutaneous adipose tissue. These disorders are rare in children and have many aetiologies. As in adults, the panniculitis can be the primary process in a systemic disorder or a secondary process that results from infection, trauma or exposure to medication. Some types of panniculitis are seen more commonly or exclusively in children, and several new entities have been described in recent years. Most types of panniculitis have the same clinical presentation (regardless of the aetiology), with tender, erythematous subcutaneous nodules.
Panniculitis , vnetje maščobnega sloja pod kožo, je redko stanje, ki se običajno kaže kot otečeni vozli ali zaplate. Erythema nodosum (EN) je najpogostejša vrsta, ki jo pogosto sprožijo različni dejavniki. Medtem ko približno 55 % primerov nima jasnega vzroka, pogosti sprožilci vključujejo okužbe, zdravila, določene bolezni, kot je sarkoidoza in vnetna črevesna bolezen, nosečnost in rak. EN se običajno pojavi pri najstnikih in mlajših odraslih, pogosteje pri ženskah. Pogosto se pojavi splošen občutek bolezni, ki traja od enega do treh tednov, s simptomi, kot so vročina in težave z zgornjimi dihali. Nato se pojavijo rdeči vozliči, običajno na zunanjih straneh rok in nog, ki povzročajo bolečino. Natančen vzrok EN ni povsem pojasnjen, vendar se domneva, da vključuje imunske komplekse v majhnih krvnih žilah maščobnega sloja, kar vodi do vnetja. Običajno biopsija pokaže vnetje v maščobni plasti brez poškodb krvnih žil. Tudi brez posebnega zdravljenja osnovnega vzroka EN pogosto izzveni sam. Zato večina bolnikov potrebuje le podporno nego za svoje simptome.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Panniculitis, an inflammation of the fat layer under the skin, is a rare condition usually showing up as swollen nodules or patches. Erythema nodosum (EN) is the most common type, often triggered by various factors. While around 55% of cases have no clear cause, common triggers include infections, medications, certain diseases like sarcoidosis and inflammatory bowel disease, pregnancy, and cancer. EN usually appears in teens and young adults, more often in females. It's often preceded by a general feeling of illness lasting one to three weeks, with symptoms like fever and upper respiratory issues. Then, red nodules appear, usually on the outer sides of arms and legs, causing pain. EN's exact cause isn't fully understood, but it's believed to involve immune complexes in small blood vessels of the fat layer, leading to inflammation. Typically, a biopsy shows inflammation in the fat layer without damage to blood vessels. Even without specific treatment for the underlying cause, EN often resolves on its own. So, most patients need only supportive care for their symptoms.
Nodozni eritem se diagnosticira klinično. Za potrditev negotove diagnoze je mogoče vzeti biopsijo in jo mikroskopsko pregledati. Za izključitev pljučnih bolezni, zlasti sarkoidoze in tuberkuloze, je treba opraviti rentgensko slikanje prsnega koša.